ABSTRACT

Objective: To evaluate the importance of molecular markers for prognosis and pathogenesis of endometrial carcinoma.

Design: Areview article.

Setting: Department of Medical Genetics and Fetal Medicine, University Hospital, Olomouc, Department of Obstetrics and Gynecology, University Hospital, Olomouc.

Methods: This article reviews the current knowledge of the molecular changes in the development of endometrial cancer, and their possible importance for the patient’s prognosis.

Conclusion: The new molecular biomarkers are apparently going to play asignificant role in the management of endometrial carcinoma treatment in the near future.

Key words: carcinoma, endometrium, marker, prognosis