Pětroš M., Ľubušký M., Šimetka O., Procházka M. Pregnant women alloimmunization of non-RhD erythrocyte antigens: review artice
ABSTRACT
Objective: The aim of this review is to give comprehensive summary on alloimmunisation of non-RhD
erythrocyte antibodies.
Design: Review.
Setting: Department of Obstetrics and Gynecology, University Hospital Ostrava, Department of
Obstetrics and Gynecology, University Hospital Olomouc.
Subject and method: Based on literature analysis using database search engines PubMed, Google Scholar,
Ovid and Proquest in field of non-RhD erytrocyte antibodies, there has been summarized up-to-date
knowledge on irregular antibodies.
Conclusion: Pregnant women alloimmunisation of non-RhD erythrocyte antigens gather importance in
conjunction with relative increase of their occurence. Profylaxis is not possible. Although these
erythrocyte antigens are able to induce antibody responce in mother and result in subsequent hemolytic
disease of fetus and newborn. There are discussed most frequent non-RhD antibodies in the paper.
Key words: alloimmunisation, non-RhD antibodies, prenatal diagnosis.