Dvorak V., Pilka R., Ľubušký M., Langová K. Prebioptické metody při screeningu karcinomu děložního hrdla. Čes. Gynek., 2014, 79 (4), s. 260-268. (Prebioptic methods in the cervical cancer screening)
ABSTRACT
Objective: To evaluate the agreement between Pap
smears, colposcopic findings and definitive excisional
specimen in patients with abnormal Pap smears.
Design: Retrospective study.
Setting: Center of outpatient gynecology and primary
care, Brno; Department of Obstetrics and Gynecology,
University Hospital, Olomouc; Department of Medical
Biophysics, Palacky University, Olomouc.
Subjects and methods of the study: This retrospective
study assessed the correlation between colposcopy and
histopathology of woman who had abnormal Pap smears.
Colposcopic chart review included participants from
2008 to 2012 who attended colposcopic clinic, center
of outpatient gynecology care, Brno.
Results: One thousand nine hundred and twenty five
patients screened by cytology, submitted to colposcopy
and subjected to cone biopsy were selected.
Cytopathological results were compared with colposcopic
findings and results obtained on the basis of histological
analyses of cone biopsy specimen. Agreement
of cytology and histopathological diagnosis was in 1199
patients (62.3%). Agreement of colposcopic diagnosis
and cervical pathology was matched in 1492 (93.5%).
Agreement of colposcopy and cytology was found in
1022 pacientek (64.1%). False negatives of cytology in
high grade lesions were in 36.4%.
Conclusion: Strength of agreement between colposcopic
diagnosis and cervical pathology was found to be very
good while for cytology high percentage of false negative
results was seen. Expert colposcopists and high quality
standard cytopathologic and bioptic laboratories are
necessary for nationwide cervical screening programmes.