Professor Marek Lubusky, MD, PhD, MHAProfessor Marek Lubusky, MD, PhD, MHA

Ľubušký M., Kudela M., Ľubušký D., Machač Š., Procházka M., Míčková I. The Effectiveness and Complications of Ovarian Trasnposition in Young Women with Cervical Cancer. Čes. Gynek., 2004, 69 (4), s. 283-286.

To assess the indications, effectiveness, and complications of ovarian transposition before pelvic irradiation for cervical cancer.
To discuss risk factors for ovarian metastasis in a transposed ovary in patients treated for cervical cancer.
To examine the incidence and risk factors of ovarian metastases in cervical carcinoma. The function of transposed ovary was also studied.
To investigate a possible difference in ovarian metastasis between squamosus cell carcinoma and adenocarcinoma of the uterine cervix and to confirm clinicopathological variables associated with the metastases.
Ovarian transposition is a safe and effective procedure for preserving ovarian function in patients treated by a radiosurgical combination. This precedure should be performed in patients <40 years of age with a small invasive cervical carcinoma (<3cm) trated by initial surgery. In such selected cases, the risk of ovarian metastasis is low. This procedure should not be performed in patients with bulky tumor and/or in patients with LVSI.
Preservation of ovarian function should be persued in patients with squamosus cell carcinoma of the cervix, provided that the patient has no other risk factor (blood vessel invasion) for ovarian metastases. Moreover, sufficient attention should be paid to the proper handling of ovarian blood vessels during surgery, in order to shield and and protect them from exposure to scattered radiation administered during postoperative radiotherapy.
The incidence of ovarian metastasis of adenocarcinoma of the uterine cervix was significantly higher than that of squamosus cell carcinoma. The incidence of adenocarcinoma was associated more closely with tumor size than clinical stage whereas it was more associated with clinical stage in squamosus cell carcinoma. The results thus suggested that the differences in ovarian metastases were caused by the different characteristics of the two types of carcinoma.

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Professor Marek Lubusky, MD, PhD, MHA

Department of Obstetrics and Gynecology
Palacky University Olomouc, Faculty of Medicine and Dentistry
University Hospital Olomouc
I. P. Pavlova 6, 77520 Olomouc, Czech Republic
Tel: +420 585 852 785
Mobil: +420 606 220 644